Intraepithelial carcinoma (Bowen disease) - Karsinom Intraepitelial (Maladi Bowen)
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Ka tipik — Karsinom Intraepitelial (Maladi Bowen) (Intraepithelial carcinoma (Bowen disease)) souvan dyagnostike kòm yon ekzema ki dire lontan epi ki pa grate.
relevance score : -100.0%
ReferencesBowen's disease (BD) se yon kalite kansè po ki kòmanse nan kouch ekstèn po a (epiderm). Li pi komen nan Caucasians e souvan rive nan zòn ki ekspoze a limyè solèy la, men li ka parèt tou nan lòt kote. BD anjeneral parèt kòm yon sèl blesi. Yo souvan konsidere BD kòm yon siy avètisman anvan yon kalite kansè po ki pi grav devlope. Pou fè dyagnostik BD, doktè anjeneral konte sou egzamen echantiyon tisi anba mikwoskòp (biopsi (biopsy)).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease sitou afekte moun ki gen po blan ki gen plis pase 60 an. Faktè risk kle yo se ekspoze alontèm ak solèy, sistèm iminitè febli, ekspoze a asenik, ak enfeksyon po HPV. Tansyon HPV 16, 18, 34, ak 48 yo lye ak maladi Bowen nan zòn jenital yo. Patisipasyon HPV nan ka ki pa jenital yo mwens klè.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Anjeneral li parèt kòm yon zòn eritematòs, kal oswa kwout, nenpòt kote sou kò a. Kote ki pi komen se pye yo.
Li ka trete ak plizyè opsyon tankou kriyoterapi, curettage, cautery, terapi fotodinamik, oswa eksizyon lezyon an.
○ Dyagnostik ak Tretman
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy